Search on: COMPLEMENT C3B INACTIVATOR PROTEINS 
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Descriptor English:   Complement C3b Inactivator Proteins 
Descriptor Spanish:   Proteínas Inactivadoras del Complemento C3b 
Descriptor Portuguese:   Proteínas Inativadoras do Complemento C3b 
Tree Number:   D12.776.124.486.274.920.325
Definition English:   Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence. 
Indexing Annotation English:   DF: C3B INACT
Pharmacological Action:   Complement Inactivating Agents
 
History Note English:   2006 (1978) 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   22142 
Unique Identifier:   D003180 

Occurrence in VHL: 		 

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